HuagongsheHuagongshe Chemistry Print Report · For research reference only
beta-Phenylisovaleric acid → 3-Methyl-3-phenylbutanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | beta-Phenylisovaleric acid | HCID 13890 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Product | 3-Methyl-3-phenylbutanoyl chloride | HCID 12867568 | 98.1% |
Reaction Steps
3-Methyl-3-phenylbutanoic acid (1.78 g, 10.0 mmol) was dissolved in thionyl chloride (5 mL, 68.5 mmol). The reaction mixture was heated at reflux for 6 hours. Concentration of the reaction mixture provided the title compound (1.93 g, 98%), which was used without additional purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-4a22026f9e2f450ab2a145771d43622f |
| Source note | uspto-grants-2013_12 |