4-Methoxyphenylacetic Acid → HCID 68749192, compound

HRID 1912959Notes

Reaction equation

HRID 1912959 reaction equation
[C:1]([C:5]1[C:6]([NH2:14])=[N:7][N:8]2[CH:13]=[CH:12][CH:11]=[N:10][C:9]=12)([CH3:4])([CH3:3])[CH3:2].[CH3:15][O:16][C:17]1[CH:22]=[CH:21][C:20]([CH2:23][C:24](O)=[O:25])=[CH:19][CH:18]=1>>[C:1]([C:5]1[C:6]([NH:14][C:24](=[O:25])[CH2:23][C:20]2[CH:21]=[CH:22][C:17]([O:16][CH3:15])=[CH:18][CH:19]=2)=[N:7][N:8]2[CH:13]=[CH:12][CH:11]=[N:10][C:9]=12)([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 76904-Methoxyphenylacetic AcidHCID 687554713-Tert-butylpyrazolo[1,5-a]pyrimidin-2-amine

Product 1

HCID 68749192HCID 68749192, compound

Procedure

The product from Example 105B and 4-methoxyphenylacetic acid were processed using the method analogous to that described in Example 137 to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 1.39 (s, 9H), 3.55 (s, 2H), 3.74 (s, 3H), 6.87-6.97 (m, 2H), 6.99 (dd, J=7.1, 4.1 Hz, 1H), 7.23-7.26 (m, 2H), 8.47 (dd, J=3.9, 1.9 Hz, 1H), 8.91 (dd, J=7.0, 1.5 Hz, 1H), 9.87 (s, 1H); MS (DCI) m/z 339 (M+H)+.

Sources & evidence

ORD record
ord-07b2a8195e14444b84a5e7ff7e721179
Source dataset
uspto-grants-2013_12
Patent number
US08609669B2

Reaction notes

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