HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,4-Dimethylpentanoic acid → N-(3-tert-butylpyrazolo[1,5-a]pyrimidin-2-yl)-4,4-dimethylpentanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,4-Dimethylpentanoic acid | HCID 14237 | — |
| Reactant | 3-Tert-butylpyrazolo[1,5-a]pyrimidin-2-amine | HCID 68755471 | — |
| Product | N-(3-tert-butylpyrazolo[1,5-a]pyrimidin-2-yl)-4,4-dimethylpentanamide | HCID 68754626 | — |
Reaction Steps
The product from Example 105B and 4,4-dimethylpentanoic acid were processed using the method analogous to that described in Example 137 to afford the title compound. 1H NMR (300 MHz, DMSO-d6) δ ppm 0.89 (s, 9H), 1.44 (s, 9H), 1.48-1.53 (m, 2H), 2.23-2.27 (m, 2H), 6.99 (dd, J=7.1, 4.0 Hz, 1H), 8.48 (dd, J=4.0, 2.0 Hz, 1H), 8.92 (dd, J=6.9, 1.8 Hz, 1H), 9.69 (s, 1H); MS (DCI) m/z 303 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609669B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-2bd52b83a3694bae9d1c0ef331377be0 |
| Source note | uspto-grants-2013_12 |