Ammonia → HCID 178490789, compound

Participants

Reaction Steps

To a solution of 29 mg of 6-(4-acetylamino-cis-cyclohexyloxy)-4-chloro-2-(4-methoxy-benzyl)-1-oxo-1,2-dihydro-isoquinoline-7-sulfonyl chloride (129, crude product) in 2 ml of THF 2 ml of 33% aqueous ammonia solution were added. After 1 h at room temperature the solvent was removed under reduced pressure and the crude product was used without further purification. Rt=1.22 min (Method C). Detected mass: 534.5 (M+H+).

Provenance & Evidence