反应详情

1.0 g (6.4 mmol) of 1-(6-chloropyridin-3-yl)-N-methylmethanamine [for the preparation, see EP 0 556 684-A1] are initially charged in 1.5 ml (1.6 g, 31.9 mmol) of hydrazine hydrate and stirred at boiling point at a bath temperature of 150° C. for 12 h. The reaction solution is cooled and concentrated, and the residue is dried under reduced pressure. This gives 1.1 g of the title compound, which is used without any further purification.

1. customtemperature of 150° C.
2. customfor 12 h
3. temperatureThe reaction solution is cooled
4. concentrationconcentrated
5. customthe residue is dried under reduced pressure
6. customThis gives 1.1 g of the title compound, which is used without any further purification