HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → tert-Butyl 6-(5-oxo-4-pyridin-3-yl-2,5-dihydro-1H-pyrazol-1-yl)pyridine-3-carboxylate hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 59280191 | HCID 59280191 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | tert-Butyl 6-(5-oxo-4-pyridin-3-yl-2,5-dihydro-1H-pyrazol-1-yl)pyridine-3-carboxylate hydrochloride | HCID 86640854 | — |
Reaction Steps
100 mg (0.3 mmol) of the compound from Example 15 are stirred in a 4 N solution of hydrogen chloride in dioxane at RT for 30 min. The solid is then filtered off and dried under high vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609698B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-352601ddf2ab46cea4799d39295e9e83 |
| Source note | uspto-grants-2013_12 |