Hydrochloric Acid → HCID 68717438, compound

Participants

Reaction Steps

400 mg (1.2 mmol) of the compound from Example 20 are stirred in 20 ml of a 4 N solution of hydrogen chloride in dioxane at RT for 30 min. The solid is filtered off and dried under high vacuum. It is then dissolved in water, and the solution is lyophilized. The lyophilizate is once more stirred with 10 ml of a 4 N solution of hydrogen chloride in dioxane for 30 min. The solid is filtered off, washed once with tert-butyl methyl ether and dried under high vacuum.

Provenance & Evidence