HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 10801230, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | 2-Bromo-4-methoxyphenylacetic acid | HCID 3963668 | — |
| Catalyst | Sulfuric Acid | HCID 1118 | — |
| Product | HCID 10801230 | HCID 10801230 | — |
Reaction Steps
To a solution of (2-bromo-4-methoxy-phenyl)-acetic acid (1.07 g, 4.37 mmol) in 25 mL MeOH was added two drops of concentrated H2SO4 and the reaction was heated to reflux. After 18 hours, the solvent was removed in vacuo to give 920 mg of (2-bromo-4-methoxy-phenyl)-acetic acid methyl ester. This material was used directly in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08609680B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-08ca7c0ee84442aabfdc67bb4bf2f14c |
| Source note | uspto-grants-2013_12 |