Hydrochloric Acid → HCID 67409470, compound

Participants

Reaction Steps

The crude 2-(2-methoxy-2-oxoethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine-3-carboxylate (39 mg, 0.16 mmol) was suspended in concentrated HCl (5 mL) and was heated at reflux for 2 hours. The reaction was cooled and concentrated in vacuo to afford the title compound (30 mg, 88%). The material was used directly without further purification. MS (ES+) 181.2 (M+H)+. Retention time: 1.26 min XBridge C18 4.6×50 mm 5 um, 5-100% acetonitrile:water (0.1% formic acid).

Provenance & Evidence