Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Cesium carbonate | HCID 10796 | — |
| Reactant | Methyl N-[6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)-3,5-dicyano-4-piperidin-1-ylpyridin-2-yl]-N-methylglycinate | HCID 66671863 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 58097231 | HCID 58097231 | — |
Reaction Steps
80 mg (0.15 mmol) of the compound from Example 47A were initially charged in 3 ml of acetonitrile, and 189 mg (0.58 mmol) of cesium carbonate were added. The mixture was stirred at 50° C. for 4 h. After cooling, the mixture was filtered and the filtrate was freed from the solvent on a rotary evaporator. The residue was dried under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08609686B2 |
|---|
| Source dataset | uspto-grants-2013_12 |
|---|
| ORD ID | ord-5a37488f0a86402695274137d2550a9c |
|---|
| Source note | uspto-grants-2013_12 |
|---|
