反应详情

18.6 g (130.87 mmol) of 4-fluoro-2-(hydroxymethyl)phenol and 42.67 g (124.32 mmol) of triphenylphosphonium hydrobromide are stirred under reflux in 186 ml of acetonitrile for 3 h. After cooling, the resulting precipitate is filtered off with suction and dried. 58 g (124 mmol, 100% of theory) of the title compound are obtained.

1. temperatureAfter cooling
2. filtrationthe resulting precipitate is filtered off with suction
3. customdried