4-Cyanopyridine → 4-Pyridinecarbonitrile, 1-oxide

HRID 1913981Notes

Reaction equation

HRID 1913981 reaction equation

[C:1]([C:3]1[CH:8]=[CH:7][N:6]=[CH:5][CH:4]=1)#[N:2].[OH:9]F>CC#N>[C:1]([C:3]1[CH:8]=[CH:7][N+:6]([O-:9])=[CH:5][CH:4]=1)#[N:2]

Participants

4

Reactant 2

HCID 75064-Cyanopyridine

HCID 123334Hypofluorous acid

Product 1

HCID 846844-Pyridinecarbonitrile, 1-oxideYield 59%

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

4-cyanopyridine was reacted with 1 equivalent of HOF.MeCN to yield 59% of 4-cyanopyridine-N-oxide.

Sources & evidence

ORD record: ord-2f01ea95d6114e338be2ca955df61184
Source dataset: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08609873B2

Reaction notes

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