HCID 52944272, compound → HCID 50899254, compound

Participants

Reaction Steps

To a solution of 8-[5-(4-t-butoxycarbonyl-piperazin-1-yl)-2-trifluoromethoxy-phenylamino]-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide (94 mg, 0.16 mmol) in dioxane (3 ml), 4M HCl in dioxane (0.89 ml, 3.42 mmol) was added. The mixture was stirred at room temperature for 3 h. The solvent was removed under reduced pressure and the crude was diluted with Et2O and decanted, to give the final compound as a hydrochloride salt in quantitative yield.

Provenance & Evidence