HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Methoxy-3-nitrophenyl)-4-methylpiperazine → HCID 24994141, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Methoxy-3-nitrophenyl)-4-methylpiperazine | HCID 59441886 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 24994141 | HCID 24994141 | 90.4% |
Reaction Steps
A solution of 1-(4-methoxy-3-nitro-phenyl)-4-methyl-piperazine (1.0 g, 4.0 mmol) in MeOH (100 mL) in the presence of Pd/C 10% (150 mg) was hydrogenated at 35 psi for 2 h. The mixture was filtered over a pad of celite and the solution was concentrated to afford 0.8 g (90% yield) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614220B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-da2faf56a50642e2a67cda9ee67d967e |
| Source note | uspto-grants-2013_12 |