反应详情

The crude rotigotine (17.2 g) prepared above in Example 9 was dissolved in 100 mL dichloromethane, and adjusted to be acidic by the addition of an aqueous HCl solution or an organic solution of hydrogen chloride or by the introduction of HCl gas. The mixture was filtered and dried to give 18.2 g rotigotine hydrochloride. Yield: 80%, Purity: 98%.

1. filtrationThe mixture was filtered
2. customdried