HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-1-Boc-3-methylpiperazine → HCID 86679980, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-1-Boc-3-methylpiperazine | HCID 7023035 | — |
| Reactant | 5-chloro-1-methyl-4-nitro-1H-pyrazole | HCID 12344836 | — |
| Product | HCID 86679980 | HCID 86679980 | — |
Reaction Steps
Following the procedure for Intermediate 10 starting from 5-chloro-1-methyl-4-nitro-1H-pyrazole from Example 1 and (S)-tert-butyl 3-methylpiperazine-1-carboxylate gave (S)-tert-butyl 4-(4-amino-1-methyl-1H-pyrazol-5-yl)-3-methylpiperazine-1-carboxylate as an orange gum (134 mg, 73% over two steps). LCMS (ES+) m/z 296 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08614206B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-c3259eb75e824fde86a89e51b09b69d0 |
| Source note | uspto-grants-2013_12 |