HCID 86680072, compound → HCID 86679999, compound

Participants

Reaction Steps

A solution of tert-butyl 5-fluoro-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepan-4-ylcarbamate (65 mg, 0.182 mmol) in MeOH (20 mL) was passed through the H-Cube® (full H2, 50° C., flow rate: 1 mL/min, 30 mm 10% Pd/C cartridge). The solvent was removed under reduced pressure to give the free amine, 5-fluoro-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepan-4-amine, as a pale yellow glass (51 mg).

Provenance & Evidence