HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methoxy-4-hydroxyphenylethylamine hydrochloride → N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-4-methyl-1,2-dithiolane-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methoxy-4-hydroxyphenylethylamine hydrochloride | HCID 11957621 | — |
| Reactant | N-(4-hydroxy-3-methoxybenzyl)-4-methyl-1,2-dithiolane-4-carboxamide | HCID 45111293 | — |
| Product | N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-4-methyl-1,2-dithiolane-4-carboxamide | HCID 45111294 | 64% |
Reaction Steps
Same method as for Compound 16 with 4-(2-aminoethyl)-2-methoxyphenol hydrochloride. 320 mg of a yellow solid are obtained (yield=64%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08617524B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-609bc5c0944a4ed7b18a31f7b0d3282c |
| Source note | uspto-grants-2013_12 |