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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1915988Generated: October 27, 2026

3-Methoxy-4-hydroxyphenylethylamine hydrochloride → N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-4-methyl-1,2-dithiolane-4-carboxamide

https://huagongshe.com/reaction/1915988

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methoxy-4-hydroxyphenylethylamine hydrochlorideHCID 11957621—
ReactantN-(4-hydroxy-3-methoxybenzyl)-4-methyl-1,2-dithiolane-4-carboxamideHCID 45111293—
ProductN-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-4-methyl-1,2-dithiolane-4-carboxamideHCID 4511129464%

Reaction Steps

Same method as for Compound 16 with 4-(2-aminoethyl)-2-methoxyphenol hydrochloride. 320 mg of a yellow solid are obtained (yield=64%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08617524B2
Source datasetuspto-grants-2013_12
ORD IDord-609bc5c0944a4ed7b18a31f7b0d3282c
Source noteuspto-grants-2013_12