反应详情

A 1 M sodium methoxyde solution was prepared by adding sodium (423 mg, 18.39 mmol) to anhydrous methanol (19 ml) with external cooling. Once all of the metal was dissolved, 4-chlorobenzaldehyde tosyl hydrazone (5.39 g, 17.51 mmol) was added and the mixture was stirred until the solid was dissolved. After stirring for a further 15 min at room temperature the methanol was removed under reduced pressure at room temperature. 5.73 g of 4-chlorobenzaldehyde tosyl hydrazone sodium salt was obtained in the form of a white powder (99% of theory).

1. dissolutionOnce all of the metal was dissolved
2. dissolutionwas dissolved
3. customwas removed under reduced pressure at room temperature