Trifluoroacetic acid → HCID 86638311, compound

Participants

Reaction Steps

Subsequently, 95 ml of trifluoroacetic acid (produced by Wako Pure Chemical Industries, Ltd.) was added to 9.22 g of the DTPA-mono-(4-(N-tert-butoxycarbonylaminomethyl)cyclohexyl)methylamide obtained above, and, after stirring the mixture for 3 hours, the reaction mixture was added dropwise to diethyl ether to precipitate the reaction product. The reaction product precipitated was collected by suction filtration, and was dried under a reduced pressure, to obtain 11.0 g of DTPA-mono-(4-(aminomethyl)cyclohexyl)methylamide as the objective compound.

Provenance & Evidence