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HRID1916096

反应详情

EQUATION

反应方程式

HRID 1916096 的结构方程式

REACTANTS

反应物

3
结构：COC(=O)Cl
HCID6586

Methyl chlorocarbonate

C2H3ClO2

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：C[Si](C)(C)CCOCn1ccc2nc(-c3cccnc3N[C@@H]3CCNC3)cnc21
HCID69812726

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)N1CC[C@@H](Nc2ncccc2-c2cnc3c(ccn3COCC[Si](C)(C)C)n2)C1
HCID58177340

未命名化合物

PROCEDURE

实验过程

(R)-3-{3-[5-(2-Trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-pyridin-2-ylamino}-pyrrolidine-1-carboxylic acid methyl ester was prepared from (R)-pyrrolidin-3-yl-{3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-pyridin-2-yl}-amine and methylchloroformate using DIPEA as base and following the general synthetic procedures described in the above Examples.