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HRID1916097

反应详情

EQUATION

反应方程式

HRID 1916097 的结构方程式

REACTANTS

反应物

3
结构：CS(=O)(=O)Cl
HCID31297

Methanesulfonyl chloride

CH3ClO2S

结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：C[Si](C)(C)CCOCn1ccc2nc(-c3cccnc3N[C@@H]3CCNC3)cnc21
HCID69812726

未命名化合物

PRODUCTS

生成物

1
结构：C[Si](C)(C)CCOCn1ccc2nc(-c3cccnc3N[C@@H]3CCN(S(C)(=O)=O)C3)cnc21
HCID58177421

未命名化合物

PROCEDURE

实验过程

((R)-1-Methanesulfonyl-pyrrolidin-3-yl)-{3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-pyridin-2-yl}-amine was prepared from (R)-pyrrolidin-3-yl-{3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-pyridin-2-yl}-amine and methanesulfonyl chloride using DIPEA as base and following the general synthetic procedures described in the above Examples.