HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 58072595, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 58072870 | HCID 58072870 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 58072595 | HCID 58072595 | — |
Reaction Steps
The title compound is synthesized according to general procedure GP3 starting from 5.9 g (22.6 mmol) 4-trifluoromethyl-5-trimethylsilanylethynyl-pyridin-2-ylamine and 1.56 g (11.3 mmol) K2CO3 in 50 mL MeOH. The product is purified by chromatography on silica gel using a DCM/MeOH gradient. Yield: 2.97 g (71%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618111B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-ada1743c50784770babf4b6073133e5a |
| Source note | uspto-grants-2013_12 |