HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → HCID 178510542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | 4-Amino-1,2-dihydropyridin-2-one | HCID 573530 | — |
| Reactant | 2-Cyanoethanethioamide | HCID 1416277 | — |
| Reactant | 1H-pyrazole-3-carbaldehyde | HCID 12218383 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | HCID 178510542 | HCID 178510542 | — |
Reaction Steps
573 mg (5.20 mmol) of 4-aminopyridin-2(1H)-one, 500 mg (5.02 mmol) of pyrazole-3-carbaldehyde and 521 mg (5.20 mmol) of 2-cyanoethanethioamide were initially charged in 25 ml of 2-propanol, 0.45 ml (7.81 mmol) of acetic acid was added and the mixture was stirred at reflux for 48 h. The precipitate was removed by filtration, and the filtrate was evaporated and reacted further without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618119B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-bee6aee1bea840cda572a3780c6b68ac |
| Source note | uspto-grants-2013_12 |