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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916582Generated: November 2, 2026

1-Methylpiperazine → 5-Bromo-2-(4-methylpiperazin-1-yl)pyridine

https://huagongshe.com/reaction/1916582

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-MethylpiperazineHCID 53167—
Reactant5-Bromo-2-iodopyridineHCID 593690—
Product5-Bromo-2-(4-methylpiperazin-1-yl)pyridineHCID 16414206—

Reaction Steps

The product is obtained analogously to Example 3.24a is from 1.5 g (5.28 mmol) 5-bromo-2-iodopyridine and 1.3 mL (11.7 mmol) N-methylpiperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-570f9e1a30774626a68a85b244e42e84
Source noteuspto-grants-2013_12