HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 10072176, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | {5-[5-(4-Chloro-phenyl)-pyridin-2-ylethynyl]-pyridin-2-yl}-(2-pyrrolidin-1-yl-ethyl)-amine | HCID 10250554 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10072176 | HCID 10072176 | — |
Reaction Steps
45 μL (0.48 mmol) acetic anhydride is added to a solution of 89 mg (0.22 mmol) {5-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-pyridin-2-yl}-(2-pyrrolidin-1-yl-ethyl)-amine in 2 mL DCM. The reaction solution is stirred for 16 h at RT. The solvent is eliminated i.vac. and further purification is carried out by HPLC-MS.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618132B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-e1ac4f9df993489193c4372b18ea5fcb |
| Source note | uspto-grants-2013_12 |