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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916642Generated: November 1, 2026

Acetone → HCID 12118321, compound

https://huagongshe.com/reaction/1916642

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetoneHCID 180—
Reactant1-(2-Chloroethyl)pyrrolidine hydrochlorideHCID 81668—
Reactant2-Bromo-5-hydroxypyridineHCID 2762865—
SolventAcetonitrileHCID 6342—
ProductHCID 12118321HCID 12118321—

Reaction Steps

The product is obtained analogously to Example 3.1 e (1:1 mixture of acetone:acetonitrile instead of DMF) from 3.90 g (22.4 mmol) 6-bromo-pyridin-3-ol and 4.25 g (25.0 mmol) N-(2-chloroethyl)-pyrrolidine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-4fdcfec1ae614544b0c9511f4fe90af3
Source noteuspto-grants-2013_12