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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916672Generated: October 31, 2026

1-(2-(4-Iodophenoxy)ethyl)pyrrolidine → 3-(4-Chloro-phenyl)-6-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylethynyl]-pyridazine

https://huagongshe.com/reaction/1916672

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-(4-Iodophenoxy)ethyl)pyrrolidineHCID 21959166—
Reactant3-(4-Chloro-phenyl)-6-ethynyl-pyridazineHCID 85969687—
Product3-(4-Chloro-phenyl)-6-[4-(2-pyrrolidin-1-yl-ethoxy)-phenylethynyl]-pyridazineHCID 59835799—

Reaction Steps

Prepared according to general working method I from 1-[2-(4-iodo-phenoxy)-ethyl]-pyrrolidine (200 mg, 0.63 mmol) and 3-(4-chloro-phenyl)-6-ethynyl-pyridazine (135 mg, 0.63 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-ddcc9b37e11d48eb925aa6033570903d
Source noteuspto-grants-2013_12