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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916758Generated: October 31, 2026

1-(2-Chloroethyl)pyrrolidine hydrochloride → 1-[2-(3-Ethynyl-phenoxy)-ethyl]-pyrrolidine

https://huagongshe.com/reaction/1916758

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Chloroethyl)pyrrolidine hydrochlorideHCID 81668—
Reactantm-EthynylphenolHCID 139144—
Product1-[2-(3-Ethynyl-phenoxy)-ethyl]-pyrrolidineHCID 85969558—

Reaction Steps

Prepared analogously to Example 18a from 1-(2-chloro-ethyl)-pyrrolidine-hydrochloride and 3-ethynyl-phenol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-cea7530cc3004b28b8367d9d83ea91a1
Source noteuspto-grants-2013_12