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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916761Generated: October 27, 2026

Potassium Carbonate → HCID 67365573, compound

https://huagongshe.com/reaction/1916761

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantPyrrolidineHCID 31268—
Reactant5-Bromo-2-(chloromethyl)-1,3-benzoxazoleHCID 14204208—
SolventWaterHCID 962—
SolventDimethylformamideHCID 6228—
ProductHCID 67365573HCID 67365573—

Reaction Steps

A solution of 2 g (8.11 mmol) 5-bromo-2-chloromethyl-benzoxazole in 30 mL DMF is combined with 2.24 g (16.22 mmol) K2CO3 and 0.9 mL (10.78 mmol) pyrrolidine and stirred for 24 hours at RT. The reaction mixture is diluted with water and extracted with EtOAc. The organic phase is dried over Na2SO4, the desiccant is filtered off and the filtrate is evaporated down.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-60132da22cba45ec88c52177cc03b648
Source noteuspto-grants-2013_12