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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916764Generated: October 31, 2026

5-Ethynyl-2-pyrrolidin-1-ylmethyl-benzoxazole → 6-(4-Chloro-phenyl)-2-(2-pyrrolidin-1-ylmethyl-benzoxazol-5-ylethynyl)-quinoline

https://huagongshe.com/reaction/1916764

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Ethynyl-2-pyrrolidin-1-ylmethyl-benzoxazoleHCID 85969588—
Reactant2-Bromo-6-(4-chloro-phenyl)-quinolineHCID 85969692—
Product6-(4-Chloro-phenyl)-2-(2-pyrrolidin-1-ylmethyl-benzoxazol-5-ylethynyl)-quinolineHCID 59835809—

Reaction Steps

Prepared analogously to Example 18d from 5-ethynyl-2-pyrrolidin-1-ylmethyl-benzoxazole and 2-bromo-6-(4-chloro-phenyl)-quinoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618132B2
Source datasetuspto-grants-2013_12
ORD IDord-4685ad6c675d498986e77673de79d131
Source noteuspto-grants-2013_12