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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1916938Generated: November 2, 2026

5-(4-Carboxyphenyl)-2-hydroxypyridine → N-[2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-4-(6-oxo-1,6-dihydro-pyridin-3-yl)-benzamide

https://huagongshe.com/reaction/1916938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Carboxyphenyl)-2-hydroxypyridineHCID 53217742—
Reactant2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenylamineHCID 59401830—
ProductN-[2-Methyl-4-(2-methyl-[1,3']bipyrrolidinyl-1'-yl)-phenyl]-4-(6-oxo-1,6-dihydro-pyridin-3-yl)-benzamideHCID 59401802—

Reaction Steps

The title compound was prepared in a manner substantially the same as example 1 by coupling 2-methyl-4-(2-methyl-[1,3′]bipyrrolidinyl-1′-yl)-phenylamine with 4-(6-oxo-1,6-dihydro-pyridin-3-yl)-benzoic acid. MS: 457.3 (M+H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618159B2
Source datasetuspto-grants-2013_12
ORD IDord-7e56ba513bbe442b988ee2ebf52f9a75
Source noteuspto-grants-2013_12