Phenol, o-mercapto-(6CI,7CI,8CI) → HCID 66593635, compound

HRID 1917011Notes

Reaction equation

HRID 1917011 reaction equation
[SH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8].[CH2:9](I)[C:10]([CH3:13])([CH3:12])[CH3:11]>>[CH2:9]([S:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[OH:8])[C:10]([CH3:13])([CH3:12])[CH3:11]

Participants

3

Reactant 2

HCID 70718Phenol, o-mercapto-(6CI,7CI,8CI)HCID 84953Propane, 1-iodo-2,2-dimethyl-

Product 1

HCID 66593635HCID 66593635, compoundYield 58%

Procedure

This compound was prepared in 58% yield from 2-mercaptophenol and neopentyl iodide according to the procedure for 1p in Example VIII. 1H NMR (CDCl3): δ 1.03 (s, 9H), 2.70 (s, 2H), 6.72 (s, 1H), 6.83-6.87 (m, 1H), 6.96 (dd, J=2.2 Hz, J=7.95, 1H), 7.21-7.26 (m, 1H), 7.46-7.48 (m, 1H); 13C NMR (CDCl3): δ 28.90, 32.56, 52.64, 114.82, 120.94, 130.74, 135.61, 156.60, 158.89;

Sources & evidence

ORD record
ord-653a7a33d1144331a37d40c081ee6fea
Source dataset
uspto-grants-2013_12
Patent number
US08618162B2

Reaction notes

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