HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromouracil → 6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromouracil | HCID 5802 | — |
| Reactant | 5-Bromo-1,3-dimethyluracil | HCID 81494 | — |
| Product | 6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione | HCID 260563 | 82% |
Reaction Steps
Synthesis of the intermediate 1c is achieved from 5-bromo-1H-pyrimidine-2,4-dione according to the operating procedure described for the synthesis of 1b (solid, yield 82%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618287B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-9096d8b0b2dc43559c194a5cc87be80f |
| Source note | uspto-grants-2013_12 |