HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Trifluoromethylbenzoyl)piperazine hydrochloride → Toluene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Trifluoromethylbenzoyl)piperazine hydrochloride | HCID 16733783 | — |
| Reactant | 6-bromo-2-methyl-2H-[1,2,4]triazine-3,5-dione | HCID 58269813 | — |
| Product | Toluene | HCID 1140 | 25% |
| Product | 2-methyl-6-[4-(2-trifluoromethyl-benzoyl)-piperazin-1-yl]-2H-[1,2,4]triazine-3,5-dione | HCID 44621494 | — |
Reaction Steps
The compound 2 (yellow powder) is prepared from the triazine 2e and from the intermediate 6a according to the synthesis method 1 in toluene (yield: 25%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618287B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-7d433ef3aee641e89a6ab149821dffd7 |
| Source note | uspto-grants-2013_12 |