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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1917098Generated: November 2, 2026

6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione → Toluene

https://huagongshe.com/reaction/1917098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dioneHCID 260563—
Reactant1-(2-Trifluoromethylbenzoyl)piperazine hydrochlorideHCID 16733783—
ProductTolueneHCID 114055%
Product2,4-dimethyl-6-[4-(2-trifluoromethyl-benzoyl)-piperazin-1-yl]-2H-[1,2,4]triazine-3,5-dioneHCID 44621497—

Reaction Steps

The compound 5 (solid) is prepared from the triazine 1b and the intermediate 6a according to the synthesis method 1 in toluene (yield: 55%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618287B2
Source datasetuspto-grants-2013_12
ORD IDord-5d595c5838814334aba6ea04c9e257df
Source noteuspto-grants-2013_12