HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromouracil → Dimethylformamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromouracil | HCID 5802 | — |
| Reactant | 1-(2-Trifluoromethylbenzoyl)piperazine hydrochloride | HCID 16733783 | — |
| Product | Dimethylformamide | HCID 6228 | 47% |
| Product | HCID 44621498 | HCID 44621498 | — |
Reaction Steps
The compound 6 (solid) is prepared from 5-bromo-1H-pyrimidine-2,4-dione and from the intermediate 6a according to the synthesis method 1 in dimethylformamide (yield: 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618287B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-939e765c7f64415ea75f42a13ddd84df |
| Source note | uspto-grants-2013_12 |