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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1917100Generated: November 3, 2026

1-(3-(Trifluoromethyl)phenyl)piperazine → 1-Butanol

https://huagongshe.com/reaction/1917100

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(3-(Trifluoromethyl)phenyl)piperazineHCID 4296—
Reactant6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dioneHCID 260563—
Product1-ButanolHCID 26363%
Product2,4-dimethyl-6-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-2H-[1,2,4]triazine-3,5-dioneHCID 58269761—

Reaction Steps

The compound 7 (solid) is prepared from the triazine 1b and from 1-(3-trifluoromethyl-phenyl)-piperazine according to the synthesis method 1 in n-butanol (yield: 63%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618287B2
Source datasetuspto-grants-2013_12
ORD IDord-3725c290575a4af3a2f6e1ae9b534903
Source noteuspto-grants-2013_12