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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1917102Generated: November 1, 2026

1-[2-(Trifluoromethyl)phenyl]piperazine → 1-Butanol

https://huagongshe.com/reaction/1917102

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[2-(Trifluoromethyl)phenyl]piperazineHCID 2777670—
Reactant6-Bromo-4-methyl-2-(4,4,4-trifluoro-butyl)-2H-[1,2,4]triazine-3,5-dioneHCID 59298833—
Product1-ButanolHCID 26382%
ProductHCID 58269812HCID 58269812—

Reaction Steps

The compound 9 (solid) is prepared from the triazine 4a and from 1-(2-trifluoromethyl-phenyl)-piperazine according to the synthesis method 1 in n-butanol (yield: 82%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618287B2
Source datasetuspto-grants-2013_12
ORD IDord-8cd52c2675624ed1be8e3da84a1ac629
Source noteuspto-grants-2013_12