4-(2-Chlorophenoxy)piperidine → 1-Butanol

Participants

Role	Name	HCID	Charge
Reactant	4-(2-Chlorophenoxy)piperidine	HCID 3864656	—
Reactant	3-(6-Bromo-4-methyl-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl)-propionitrile	HCID 59298828	—
Product	1-Butanol	HCID 263	58%
Product	3-{6-[4-(2-chloro-phenoxy)-piperidin-1-yl]-4-methyl-3,5-dioxo-4,5-dihydro-3H-[1,2,4]triazin-2-yl}-propionitrile	HCID 44621505	—

The compound 23 (oil) is prepared from the triazine 3a and from the intermediate 8a according to the synthesis method 1 in n-butanol (yield: 58%).