6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione → 1-Butanol

HRID 1917106Notes

Reaction equation

HRID 1917106 reaction equation
Br[C:2]1[C:3](=[O:11])[N:4]([CH3:10])[C:5](=[O:9])[N:6]([CH3:8])[N:7]=1.[Cl:12][C:13]1[CH:25]=[CH:24][CH:23]=[CH:22][C:14]=1[O:15][CH:16]1[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]1>>[Cl:12][C:13]1[CH:25]=[CH:24][CH:23]=[CH:22][C:14]=1[O:15][CH:16]1[CH2:21][CH2:20][N:19]([C:2]2[C:3](=[O:11])[N:4]([CH3:10])[C:5](=[O:9])[N:6]([CH3:8])[N:7]=2)[CH2:18][CH2:17]1.[CH2:14]([OH:15])[CH2:13][CH2:25][CH3:24]

Participants

4

Procedure

The compound 27 (solid) is prepared from the triazine 1b and from the intermediate 8a according to the synthesis method 1 in n-butanol (yield: 60%).

Sources & evidence

ORD record
ord-f381bceee48b4c6592cb6155e1d75349
Source dataset
uspto-grants-2013_12
Patent number
US08618287B2

Reaction notes

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