6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione → 1-Butanol

Participants

Role	Name	HCID	Charge
Reactant	6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione	HCID 260563	—
Reactant	4-(2-Chloro-5-fluorophenoxy)piperidine	HCID 16732741	—
Product	1-Butanol	HCID 263	77%
Product	6-[4-(2-chloro-5-fluoro-phenoxy)-piperidin-1-yl]-2,4-dimethyl-2H-[1,2,4]triazine-3,5-dione	HCID 44621510	—

The compound 30 (solid) is prepared from the triazine 1b and from the intermediate 8b according to the synthesis method 1 in n-butanol (yield: 77%).