HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-1,3-dimethyluracil → 1-Butanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-1,3-dimethyluracil | HCID 81494 | — |
| Reactant | 4-(2-Chlorophenoxy)piperidine | HCID 3864656 | — |
| Product | 1-Butanol | HCID 263 | 17% |
| Product | 5-[4-(2-chloro-phenoxy)-piperidin-1-yl]-1,3-dimethyl-1H-pyrimidine-2,4-dione | HCID 58269776 | — |
Reaction Steps
The compound 35 (oil) is prepared from the uracil 1c and from the intermediate 8a according to the synthesis method 1 in n-butanol (yield: 17%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618287B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-f1380917353f47e297d8fafe1ee180f1 |
| Source note | uspto-grants-2013_12 |