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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1917109Generated: November 4, 2026

6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione → 1-Butanol

https://huagongshe.com/reaction/1917109

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Bromo-2,4-dimethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dioneHCID 260563—
Reactant3-[2-(Trifluoromethyl)phenoxy]pyrrolidineHCID 45075487—
Product1-ButanolHCID 26360%
Product2,4-dimethyl-6-[3-(2-trifluoromethyl-phenoxy)-pyrrolidin-1-yl]-2H-[1,2,4]triazine-3,5-dioneHCID 58269794—

Reaction Steps

The compound 37 (solid) is prepared from the triazine 1b and from the intermediate 11a according to the synthesis method 1 in n-butanol (yield: 60%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618287B2
Source datasetuspto-grants-2013_12
ORD IDord-6bff831ede6d4c909a7741940725d4f3
Source noteuspto-grants-2013_12