Dichloromethane → Trifluoroacetic acid

HRID 191711Notes

Reaction equation

HRID 191711 reaction equation
[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH2:10][CH2:11][S:12][S:13][CH2:14][CH2:15][NH:16][C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23].[Cl:31][CH2:32][Cl:33].[F:24][C:25]([C:26](=[O:27])[OH:28])([F:29])[F:30]>>[C:1]([c:2]1[cH:3][n:4][cH:5][cH:6][cH:7]1)(=[O:8])[NH:9][CH2:10][CH2:11][S:12][S:13][CH2:14][CH2:15][NH2:16].[F:24][C:25]([C:26](=[O:27])[OH:28])([F:29])[F:30]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 86651799Tert-butyl 2-(2-(2-(nicotinamido)ethyl)disulfanyl)ethylcarbamate

Product 2

HCID 6422Trifluoroacetic acidHCID 58173193N-[2-(2-aminoethyldisulfanyl)ethyl]pyridine-3-carboxamide

Sources & evidence

ORD record
ord-ba9f2898a10d4cf1bd0149844d6bb79b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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