HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(2-Chloro-5-fluorophenoxy)piperidine → 6-(4-(2-chloro-5-fluorophenoxy)piperidin-1-yl)-2-methyl-1,2,4-triazine-3,5(2H, 4H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(2-Chloro-5-fluorophenoxy)piperidine | HCID 16732741 | — |
| Reactant | 6-bromo-2-methyl-2H-[1,2,4]triazine-3,5-dione | HCID 58269813 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 6-(4-(2-chloro-5-fluorophenoxy)piperidin-1-yl)-2-methyl-1,2,4-triazine-3,5(2H, 4H)-dione | HCID 58269755 | — |
Reaction Steps
The compound 90 (white powder) is prepared from the triazine 2e and from the intermediate 8b according to the synthesis method 1 in toluene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08618287B2 |
| Source dataset | uspto-grants-2013_12 |
| ORD ID | ord-22a6e705493244b1b056be0564d539e5 |
| Source note | uspto-grants-2013_12 |