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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1917120Generated: November 3, 2026

6-bromo-2-methyl-2H-[1,2,4]triazine-3,5-dione → 4-(2-Chlorophenoxy)piperidine

https://huagongshe.com/reaction/1917120

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-bromo-2-methyl-2H-[1,2,4]triazine-3,5-dioneHCID 58269813—
Reactant4-(5-Bromo-2-chlorophenoxy)piperidineHCID 64011285—
Product4-(2-Chlorophenoxy)piperidineHCID 3864656—
Product6-(4-(5-bromo-2-chlorophenoxy)piperidin-1-yl)-2-methyl-1,2,4-triazine-3,5(2H, 4H)-dioneHCID 58269781—

Reaction Steps

The compound 92 (yellow powder) is prepared from the triazine 2e and from 4-(5-bromo-2-chlorophenoxy)piperidine (obtained as under the preparative conditions of intermediate 8a) according to the synthesis method 1 in toluene.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618287B2
Source datasetuspto-grants-2013_12
ORD IDord-e717bfc2cd5d40ca8ffcc926abcd6d90
Source noteuspto-grants-2013_12