Hydrochloric Acid → HCID 178489739, compound

HRID 1917509Notes

Reaction equation

HRID 1917509 reaction equation
CC1(C)O[C@@H](CC[O:9]/[N:10]=[C:11]2\[NH:12][C@@H:13]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][C:24]=3[C:30]3[CH:35]=[CH:34][CH:33]=[C:32]([O:36][CH3:37])[N:31]=3)[CH2:14][C:15]3[N:16]=[C:17]([NH2:22])[N:18]=[C:19]([CH3:21])[C:20]\2=3)CO1.Cl>>[NH2:22][C:17]1[N:18]=[C:19]([CH3:21])[C:20]2=[C:15]([CH2:14][C@H:13]([C:23]3[CH:28]=[CH:27][C:26]([F:29])=[CH:25][C:24]=3[C:30]3[CH:35]=[CH:34][CH:33]=[C:32]([O:36][CH3:37])[N:31]=3)[NH:12]/[C:11]/2=[N:10]\[OH:9])[N:16]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178489726HCID 178489726, compound

Product 1

HCID 178489739HCID 178489739, compound

Procedure

Deprotection of 86h was achieved by treating with diluted HCl as described in Example 85 to yield Compound 37.

Sources & evidence

ORD record
ord-93670ea14d8a4b77822563566d85989e
Source dataset
uspto-grants-2013_12
Patent number
US08618290B2

Reaction notes

Loading…