反应详情

温度

23 °C

To a solution of 4-isopropylpyridine (3.12 g, 25.7 mmol) in acetonitrile (25 mL) is added 2-bromo-4′-chloro-acetophenone (6.01 g, 25.7 mmol). The mixture is stirred at 23° C. overnight then the resulting precipitate is filtered, collected, and dried to afford the title intermediate (7.10 g, 78%).

1. filtrationthe resulting precipitate is filtered
2. customcollected
3. customdried