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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1917598Generated: November 2, 2026

p-Chlorophenacyl bromide → HCID 86659071, compound

https://huagongshe.com/reaction/1917598

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Chlorophenacyl bromideHCID 68303—
Reactant4-IsopropylpyridineHCID 69674—
SolventAcetonitrileHCID 6342—
ProductHCID 86659071HCID 8665907178%

Reaction Conditions

Temperature23 °C

Reaction Steps

To a solution of 4-isopropylpyridine (3.12 g, 25.7 mmol) in acetonitrile (25 mL) is added 2-bromo-4′-chloro-acetophenone (6.01 g, 25.7 mmol). The mixture is stirred at 23° C. overnight then the resulting precipitate is filtered, collected, and dried to afford the title intermediate (7.10 g, 78%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08618300B2
Source datasetuspto-grants-2013_12
ORD IDord-a6e9c2cd01284b138aecab870f1b0c3d
Source noteuspto-grants-2013_12